Fibroblast growth factor 23 levels before and after renal transplantation
نویسندگان
چکیده
منابع مشابه
FGF-23 Levels before and after Renal Transplantation
Phosphatonin fibroblast growth factor-23 (FGF-23) is involved in phosphate (P) excretion and vitamin D metabolism. Recently, FGF-23 has been suggested to be responsible for the hypophosphatemia and inappropriately low calcitriol levels observed after renal transplantation. We performed a prospective study to investigate FGF-23 levels in patients with end-stage renal disease before and after ren...
متن کاملThe role of fibroblast growth factor 23 in renal disease.
Activating mutations in the fibroblast growth factor 23 (FGF23) gene were identified as the cause of autosomal dominant hypophosphataemic rickets (ADHR) [1]. This secreted protein was later shown to play a role in both physiological and pathological phosphate handling. FGF23 may be the key pathogenetic molecule in three different diseases with hypophosphataemia and inappropriate regulation of v...
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BACKGROUND Fibroblast growth factor -23 (FGF-23) is a key regulator of mineral metabolism. It regulates renal phosphate (Pi) reabsorption and calcitriol synthesis, and has an inhibitory effect on parathyroid hormone (PTH) secretion. FGF-23 increases early in chronic kidney disease (CKD), but the regulation of FGF-23 in mild -to -moderate renal dysfunction is not fully understood. METHODS Nine...
متن کاملHow fibroblast growth factor 23 works.
There is a discontinuum of hereditary and acquired disorders of phosphate homeostasis that are caused by either high or low circulating levels of the novel phosphaturic hormone fibroblastic growth factor 23 (FGF23). Disorders that are caused by high circulating levels of FGF23 are characterized by hypophosphatemia, decreased production of 1,25-dihydroxyvitamin D, and rickets/osteomalacia. On th...
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Cardiovascular diseases are the leading cause of morbidity and mortality in both dialysis dependent patients and those either waiting for or following up after renal transplantation. Concerns about the risk of contrast-induced acute kidney injury (CI-AKI) associated with coronary angiography in patients with stage 4 or 5 chronic kidney disease (CKD) have sometimes resulted in coronary angiograp...
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ژورنال
عنوان ژورنال: The Egyptian Journal of Internal Medicine
سال: 2016
ISSN: 1110-7782,2090-9098
DOI: 10.4103/1110-7782.193887